Paraneoplastic Hormonal Syndromes
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[Paraneoplastic hormonal syndromes].
We can define paraneoplastic syndromes as a combination of effects occurring far from the original location of the tumour and independently from the local repercussion of its metastases. Paraneoplastic hormonal syndromes depend on the secretion of hormonal peptides or their precursors, cytokines and, more rarely, thyroidal hormones and Vitamin D, which act in an endocrine, paracrine or autocrin...
full textParaneoplastic cerebellar ataxia and the paraneoplastic syndromes.
Paraneoplastic cerebellar ataxia, also known as paraneoplastic cerebellar degeneration, is one of the wide array of paraneoplastic neurological syndromes in which neurological symptoms are indirectly caused by an underlying malignancy, most commonly gynecological, breast, or lung cancer or Hodgkin's lymphoma. We describe a patient with severe cerebellar dysfunction attributed to a paraneoplasti...
full textParaneoplastic neurological syndromes
Necrobiotic xanthogranuloma This presents as multiple sharply demarcated, indurated, non-tender dermal or subcutaneous nodules and plaques. Periorbital involvement is common. Lesions vary from violaceous to red orange, and enlarge to form infiltrative plaques that may show central atrophy. Though most of the lesions are asymptomatic, some may be pruritic or painful. Ulceration and scarring are ...
full textParaneoplastic neurological syndromes
Paraneoplastic neurological syndromes are immune-mediated erroneous attacks on the central or peripheral nervous systems, or both, directed originally against the tumour itself. They have been known for more than 40 years, but recently the discovery of new subgroups of paraneoplastic encephalitis syndromes with a remarkably good response to immune therapy has ignited new clinical and scientific...
full textParaneoplastic Rheumatic Syndromes
Objective: Review of the literature addressing the rheumatic manifestations of various malignancies as well as of common chemotherapeutic agents. Methods: A literature search was performed to identify key articles regarding the association of rheumatic disease with malignancy. Results: Our review focused on the association of rheumatic disease with malignancy, paraneoplastic syndromes with rheu...
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Journal title
volume 2 issue 4
pages 287- 295
publication date 1974-04
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